Myelin basic protein (MBP) is reported to account for about 30% of myelin protein in the central nervous system. MBP can induce experiment allergic encephalomyelitis (EAE), a delayed-type hypersensitivity diseases disease mediated by T lymphocytes. The reactions to different fragments of 170 amino acid peptides are presented in each animal genus. And four different subtunit determined by cDNA cloning. Beside, , the four isomers are the same expect to two insert, or deleted peptide fragments which encode by code 2 and code 5.It has been reported that myelin basic proteins are expressed in Oligodendrocyte ,brain and white matter of the spinal cord myelin as well as peripheral nerve. But it is expressed less in gray matter of the spinal cord myelin.
[As Figure shows]
Ganglioglioma tissue stained with Myelin Basic Protein
This antibody is intended for use in Immunohistochemical applications on formalin-fixed paraffin-embedded tissues (FFPE). The clinical interpretation of any staining or its absence should be complemented by morphological studies using proper controls and should be evaluated within the context of the patient’s clinical history and other diagnostic tests by a qualified pathologist.
Product Name | Myelin Basic Potein(7H11),MMab |
Catalog No. | CMM-0320 |
Intended Use | IVD, RUO |
Species Reactivity | Human; others not tested |
Cellular Localization | Cytoplasm / Nucleus |
Antibody Type | Mouse Monoclonal |
Clone | 7H11 |
Format and Volume | Ready-to-use: 1mL, 3mL, 6mL Concentrated: 0.1mL, 0.2mL and 1mL |
IVD Datasheet (IFU) | ↕️ Download |
RUO Datasheet (IFU) | ↕️ Download |
SDS sheet | check with sales |
Store at 2~8°C. Avoid freezing.
Maintain temperature below room temperature during transport, ensuring it does not exceed one week.