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LEF-1(EP310),RMab
Lymphatic enhancer factor (LEF-1) belongs to the highly migrating family of components, which plays an important role in cell proliferation, differentiation and apoptosis as a transcription factor-mediated of Wnt signaling pathway in the nucleus of the cell.In chronic lymphocytic leukemia, the high expression of LEF-1 is associated with the development of the disease and adverse prognosis. LEF-1 can be detected the positive exprssion of immunohistochemistry in all malignant cells of chronic lymphocytic leukemia or small lymphocytic lymphocytic lymphocytic disease. LEF-1 had 50% positive expression in follicle lymphoma with high differentiation and 38% positive expression in large B-cell lymphoma,but not in mantle cell lymphoma and marginal zone lymphoma.
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Staining Tissue
[As Figure shows]
Lymphoma tissue stained with LEF1
[Intended Use]
Lymphatic enhancer factor (LEF-1) belongs to the highly migrating family of components, which plays an important role in cell proliferation, differentiation and apoptosis as a transcription factor-mediated of Wnt signaling pathway in the nucleus of the cell.In chronic lymphocytic leukemia, the high expression of LEF-1 is associated with the development of the disease and adverse prognosis. LEF-1 can be detected the positive exprssion of immunohistochemistry in all malignant cells of chronic lymphocytic leukemia or small lymphocytic lymphocytic lymphocytic disease. LEF-1 had 50% positive expression in follicle lymphoma with high differentiation and 38% positive expression in large B-cell lymphoma,but not in mantle cell lymphoma and marginal zone lymphoma.
[Specifications]
| Product Name | LEF-1(EP310),RMab |
| Catalog No. | CLR-0080 |
| Intended Use | IVD, RUO |
| Species Reactivity | Human; others not tested |
| Cellular Localization | Cytoplasm / Nucleus |
| Antibody Type | Rabbit Monoclonal |
| Clone | EP310 |
| Format and Volume | Ready-to-use: 1mL, 3mL, 6mL Concentrated: 0.1mL, 0.2mL and 1mL |
[Datasheets & SDS]
| IVD Datasheet (IFU) | ↕️ Download |
| RUO Datasheet (IFU) | ↕️ Download |
| SDS sheet | check with sales |
[Storage and Validity]
Store at 2~8°C. Avoid freezing.
Maintain temperature below room temperature during transport, ensuring it does not exceed one week.
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