2025-06-11
By celnovte
As antibody-drug conjugates (ADCs) gain traction in modern oncology, the need for reliable IHC markers for ADC therapy has become a critical factor in enabling precision treatment. Accurate detection of ADC targets in tumor tissue is the first and most vital step in determining therapeutic eligibility.
Celnovte—a trusted leader in immunohistochemistry—introduces its ADC Companion Diagnostic Antibody Series, developed for clinical use in ADC biomarker screening, pathology laboratories, and drug development programs.
Unlike standard IVD antibodies, Celnovte’s ADC diagnostic antibodies are:
Whether you’re a hospital, CRO, or drug developer, these antibodies are engineered to meet the real-world demands of ADC biomarker detection.
Celnovte’s IHC markers include both FDA-approved and investigational ADC targets, supporting a robust diagnostic portfolio across multiple cancer types:
ADC Target | Cancer Types | Related ADC Drugs |
---|---|---|
HER2 | Breast, gastric, lung | Enhertu, Kadcyla |
TROP2 | TNBC, NSCLC | Trodelvy |
Claudin18.2 | Gastric, pancreatic | Zolbetuximab |
Nectin-4 | Urothelial, breast | Padcev |
HER3 | NSCLC | Patritumab Deruxtecan |
B7-H3 | Neuroblastoma, lung | MGC018, DS-7300 (investigational) |
B7-H4 | Ovarian, breast | ABBV-428, SGN-B7H4V (investigational) |
FRα (Folate Receptor Alpha) | Ovarian, NSCLC | Mirvetuximab soravtansine |
c-Met | Liver, gastric, lung | Telisotuzumab vedotin (investigational) |
These IHC biomarkers for ADCs are rigorously optimized for automated staining platforms and clinically validated.
To streamline clinical workflows, Celnovte offers an end-to-end solution for ADC IHC diagnostics:
This fully integrated platform accelerates the companion diagnostic workflow for ADC therapy—from biopsy to clinical decision.
Celnovte’s IHC antibodies are actively used in:
With growing demand for CDx IHC markers for ADCs, Celnovte provides clinical-grade reagents backed by scientific collaboration and international validation.
Every successful ADC therapy begins with the right IHC biomarker. At Celnovte, we deliver more than antibodies—we deliver validated, ready-to-use diagnostic tools that drive precision oncology.
🔍 Whether you’re searching for IHC markers for ADCs, building a companion diagnostic assay, or targeting new tumor types—our portfolio is built for speed, accuracy, and clinical reliability.
📩 Contact us today for technical data sheets, validation reports, or to request a trial sample set of our ADC IHC markers.