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CNT200 CNT200 In Situ Hybridization
The CNT200 In Situ Hybridization System harnesses the powerful principle of nucleic acid hybridization, developed from DNA replication research. In situ hybridization enables researchers to visualize, localize, and semi-quantitatively analyze nucleic acid sequences directly within tissue sections or cells.By using labeled DNA or RNA probes that hybridize to complementary sequences within samples, ISH provides a direct, simple, and reliable method to study gene localization and expression. This technique offers high sensitivity and specificity, making it essential for modern research in cell biology, molecular biology, and pathology.
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Product Features
What is In Situ Hybridization (ISH)?
The CNT200 In Situ Hybridization System harnesses the powerful principle of nucleic acid hybridization, developed from DNA replication research. In situ hybridization enables researchers to visualize, localize, and semi-quantitatively analyze nucleic acid sequences directly within tissue sections or cells.
By using labeled DNA or RNA probes that hybridize to complementary sequences within samples, ISH provides a direct, simple, and reliable method to study gene localization and expression. This technique offers high sensitivity and specificity, making it essential for modern research in cell biology, molecular biology, and pathology.
Key Features of the CNT200
✅ Three Operating Modes for Flexible Applications
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Denaturation & Hybridization Mode
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Hybridization Mode
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Multipoint Mode
With support for up to 120 custom work programs, researchers can precisely tailor protocols for their experimental needs.
✅ High-Precision Temperature and Humidity Control
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Temperature range: 35~99℃, ensuring optimal conditions for hybridization and denaturation steps.
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Rapid and accurate temperature control with real-time display on the user-friendly screen.
✅ Superior Sample Capacity
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Simultaneous processing of up to 12 slides.
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Fully sealed upper cover design and automatic humidification maintain optimal temperature and humidity throughout the hybridization process.
✅ Integrated Automation
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Automated completion of denaturation and hybridization steps, enhancing consistency and reproducibility in every run.
Applications
🔬 Gene Mapping & Genome Evolution
Locate and characterize gene-specific mRNA transcripts within cells, advancing insights into gene expression and genomic evolution.
🔬 Pathogen Detection
Identify and localize viral DNA/RNA in infected tissues (e.g., EBV mRNA, HPV, CMV), providing critical diagnostic information.
🔬 Oncogene and Tumor Suppressor Analysis
Detect expression changes of oncogenes and tumor suppressor genes at the transcriptional level for cancer research.
🔬 Chromosome Analysis
Accurately identify chromosomal abnormalities, such as aneuploidy and translocations, through FISH and CISH protocols.
Why Choose the CNT200?
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Enhanced Accuracy: Microprocessor-controlled automation minimizes human error and ensures precision in every experiment.
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Robust Design: Engineered to meet the rigorous demands of research and clinical laboratories.
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User-Centric Operation: Intuitive interface and customizable protocols cater to both routine and advanced applications.
Specification
| Specification | Details |
| Temp Control | Room +5°C ~ 99°C |
| Temp Setting Range | 35°C ~ 99°C |
| Processing Time Range | 1 min ~ 99 h 59 min |
| Temp Control Accuracy | < ±1°C |
| Temp Uniformity | ±1°C |
| Heating Time | < 2 min |
| Cooling Time | < 6 min |
| Maximum Sample | 12 pieces |
| Dimensions (L x W x H) | 480 x 245 x 145 mm |
| Weight | 7 kg |
| Ambient Temp | 5°C ~ 35°C |
| Ambient Humidity | 20% ~ 80% |
| Power | AC220V/50Hz or AC110V/60Hz |
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