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CD44 V6(VFF-7),MMab
The CD44 molecule belongs to the cell adhesion molecule family and is widely found in normal and malignant cells of epithelium, mesothelium and hematopoietic tissue.It has been reported that the expression of the splice variant of the specific cell adhesion molecule CD44 is associated with the metastasis of some human malignancies, such as breast cancer.In the literature (Fox SB et al.), the expression of complex types of CD44 variants in different tumors was compared with the expression of CD44 in normal cells.Observed in ductal epithelial origin of breast cancer, CD44 variants in vitro show son has high level expression of CD44 in normal breast ductal epithelial not to express, on the contrary, it is reported that many in the normal gastrointestinal epithelium CD44 variants show low level expression, they happen in lower expression of colon cancer, and the expression of CD44 variants present a different level, normal epithelial cells in the respiratory tract CD44 variants show high levels of expression, the epithelial expressing the same variants in lung cancer and the expression level is similar.
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Staining Tissue
[As Figure shows]
Invasive epithelial carcinoma of the bladder wall tissue stained with CD44V6
[Intended Use]
The CD44 molecule belongs to the cell adhesion molecule family and is widely found in normal and malignant cells of epithelium, mesothelium and hematopoietic tissue.It has been reported that the expression of the splice variant of the specific cell adhesion molecule CD44 is associated with the metastasis of some human malignancies, such as breast cancer.In the literature (Fox SB et al.), the expression of complex types of CD44 variants in different tumors was compared with the expression of CD44 in normal cells.Observed in ductal epithelial origin of breast cancer, CD44 variants in vitro show son has high level expression of CD44 in normal breast ductal epithelial not to express, on the contrary, it is reported that many in the normal gastrointestinal epithelium CD44 variants show low level expression, they happen in lower expression of colon cancer, and the expression of CD44 variants present a different level, normal epithelial cells in the respiratory tract CD44 variants show high levels of expression, the epithelial expressing the same variants in lung cancer and the expression level is similar.
[Specifications]
| Product Name | CD44 V6(VFF-7),MMab |
| Catalog No. | CCM-0610 |
| Intended Use | IVD, RUO |
| Species Reactivity | Human; others not tested |
| Cellular Localization | Cytoplasm / Nucleus |
| Antibody Type | Mouse Monoclonal |
| Clone | VFF-7 |
| Format and Volume | Ready-to-use: 1mL, 3mL, 6mL Concentrated: 0.1mL, 0.2mL and 1mL |
[Datasheets & SDS]
| IVD Datasheet (IFU) | ↕️ Download |
| RUO Datasheet (IFU) | ↕️ Download |
| SDS sheet | check with sales |
[Storage and Validity]
Store at 2~8°C. Avoid freezing.
Maintain temperature below room temperature during transport, ensuring it does not exceed one week.
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