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Alpha-1-Antitrypsin(AAT)
Alpha-1-antitrypsin is synthesized in the liver and is present in serum and tissue fluid as a protease inhibitor, especially as an elastase inhibitor.Its main function is to neutralize the release of elastase by neutrophils in the inflammatory response.The deficiency of Alpha-1-antitrypsin may lead to lung failure to inhibit tissue destruction induced by elastase. Alpha-1-antitrypsin deficiency is associated with acinar emphysema and liver disease.In the liver, deficiency of c-1-antitrypsin may cause neonatal hepatitis or cirrhosis of the liver in some individuals during adolescence or adulthood.
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Staining Tissue
- As Figure Shows:
Tonsil tissue stained with AAT
Specification
|
CODE |
WORKING SOLUTION |
|||
|
CAR-0110 |
SPECIFICATION |
1ml |
3ml |
6ml |
More Info
Clone: Polyclonal
Source: Rabbit
Localization: Cytoplasm
Pretreatment: Thermal remediation
Applicable tissue: Paraffin section/Frozen section
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