MSH6 is an important member of the mismatch repair family and is positioned on chromosome 2 P arm 16 point. The DNA length is 23806BP, while the main function is to correct base pair mismatch and small fragment insertion and deficiency. When DNA is mismatched, MSH6 protein and MSH2 protein combine to produce A MutS-α heterodimer that can be identified for the mismatch site. This The heterodimer is combined with the mismatch site and initiates the mismatch repair process, thus ensuring the stability of the microsatellite.
Colon adenocarcinoma tissue stained with MSH6
MSH6 is an important member of the mismatch repair family and is positioned on chromosome 2 P arm 16 point. The DNA length is 23806BP, while the main function is to correct base pair mismatch and small fragment insertion and deficiency. When DNA is mismatched, MSH6 protein and MSH2 protein combine to produce A MutS-α heterodimer that can be identified for the mismatch site. This The heterodimer is combined with the mismatch site and initiates the mismatch repair process, thus ensuring the stability of the microsatellite.
Product Name | MSH6(C5D11),MMab |
Catalog No. | CMM-0202 |
Intended Use | IVD, RUO |
Species Reactivity | Human; others not tested |
Cellular Localization | Cytoplasm / Nucleus |
Antibody Type | Mouse Monoclonal |
Clone | C5D11 |
Format and Volume | Ready-to-use: 1mL, 3mL, 6mL Concentrated: 0.1mL, 0.2mL and 1mL |
IVD Datasheet (IFU) | ↕️ Download |
RUO Datasheet (IFU) | ↕️ Download |
SDS sheet | check with sales |
Store at 2~8°C. Avoid freezing.
Maintain temperature below room temperature during transport, ensuring it does not exceed one week.