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TTF-1 (SPT24), MMab
Thyroid Transcription Factor-1 (TTF-1) is a member of the homodomain transcription factor family, which plays a role in regulating gene expression in thyroid, lung and brain tissues. It is reported that TTF-1 is expressed in more than 90% of lung small cell carcinomas and 75% of lung non-small cell carcinomas, but not expressed in typical lung carcinoid tumors. TTF-1 is also expressed in follicular variant of papillary thyroid carcinoma (FV-PTC) and goiter (a type of non-malignant and non-toxic goiter), but not expressed in anaplastic thyroid cancer.
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Staining Tissue
[As Figure shows]
FVPTC tissue stained with TTF-1
[Intended Use]
Thyroid Transcription Factor-1 (TTF-1) is a member of the homodomain transcription factor family, which plays a role in regulating gene expression in thyroid, lung and brain tissues. It is reported that TTF-1 is expressed in more than 90% of lung small cell carcinomas and 75% of lung non-small cell carcinomas, but not expressed in typical lung carcinoid tumors. TTF-1 is also expressed in follicular variant of papillary thyroid carcinoma (FV-PTC) and goiter (a type of non-malignant and non-toxic goiter), but not expressed in anaplastic thyroid cancer.
[Specifications]
| Product Name | TTF-1 (SPT24), MMab |
| Catalog No. | CTM-0261 |
| Intended Use | IVD, RUO |
| Species Reactivity | Human; others not tested |
| Cellular Localization | Cytoplasm / Nucleus |
| Antibody Type | Mouse Monoclonal |
| Clone | 8G7G3/1 |
| Format and Volume | Ready-to-use: 1mL, 3mL, 6mL Concentrated: 0.1mL, 0.2mL and 1mL |
[Datasheets & SDS]
| IVD Datasheet (IFU) | ↕️ Download |
| RUO Datasheet (IFU) | ↕️ Download |
| SDS sheet | check with sales |
[Storage and Validity]
Store at 2~8°C. Avoid freezing.
Maintain temperature below room temperature during transport, ensuring it does not exceed one week.
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