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SOX-10, anti-rabbit, EP268
SOX-10 (Sry-relaed HMG-BOX gene 10) is a nuclear transcription factor involved in the development of nerves and the differentiation of melanocyte cell lines. It has recently been shown to be a sensitive marker for melanoma (including conventional, fusiform, and connective tissue hyperplasia). SOX-10 is expressed in 97% of melanomas and 49% of malignant schwannomas. SOX-10 is often expressed to be positive in connective tissue hyperplasia and spindle cell melanoma, but negative in HMB45 and MelanA.
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Staining Tissue
- As Figure shows:
Malignant melanoma tissue stained with SOX-10
Specification
|
CODE |
WORKING SOLUTION |
CONCENTRATED SOLUTION |
||||
|
CSR-0180 |
SPECIFICATION |
1ml |
3ml |
6ml |
0.1ml |
0.2ml |
More Info
Clone: EP268
Source: Rabbit
Localization: Nucleus
Pretreatment: Thermal remediation
Applicable tissue: Paraffin section
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