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SOX-10(EP268),RMab
SOX-10 (Sry-relaed HMG-BOX gene 10) is a nuclear transcription factor involved in the development of nerves and the differentiation of melanocyte cell lines. It has recently been shown to be a sensitive marker for melanoma (including conventional, fusiform, and connective tissue hyperplasia). SOX-10 is expressed in 97% of melanomas and 49% of malignant schwannomas. SOX-10 is often expressed to be positive in connective tissue hyperplasia and spindle cell melanoma, but negative in HMB45 and MelanA.
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Staining Tissue
[As Figure shows]
Malignant melanoma tissue stained with SOX-10
[Intended Use]
SOX-10 (Sry-relaed HMG-BOX gene 10) is a nuclear transcription factor involved in the development of nerves and the differentiation of melanocyte cell lines. It has recently been shown to be a sensitive marker for melanoma (including conventional, fusiform, and connective tissue hyperplasia). SOX-10 is expressed in 97% of melanomas and 49% of malignant schwannomas. SOX-10 is often expressed to be positive in connective tissue hyperplasia and spindle cell melanoma, but negative in HMB45 and MelanA.
[Specifications]
| Product Name | SOX-10(EP268),RMab |
| Catalog No. | CSR-0180 |
| Intended Use | IVD, RUO |
| Species Reactivity | Human; others not tested |
| Cellular Localization | Cytoplasm / Nucleus |
| Antibody Type | Rabbit Monoclonal |
| Clone | EP268 |
| Format and Volume | Ready-to-use: 1mL, 3mL, 6mL Concentrated: 0.1mL, 0.2mL and 1mL |
[Datasheets & SDS]
| IVD Datasheet (IFU) | ↕️ Download |
| RUO Datasheet (IFU) | ↕️ Download |
| SDS sheet | check with sales |
[Storage and Validity]
Store at 2~8°C. Avoid freezing.
Maintain temperature below room temperature during transport, ensuring it does not exceed one week.
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