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SMAD4/DPC4
SMAD4 gene is located on chromosome 18q21.1. The gene transcription has a total length of 2680 bp, contains 552 amino acids, and has a relative molecular weight of 60 kD. SMAD4 junction region is necessary for other SMADs to bind to it. SMADs are the key link that TGF-β signal enters nucleus from cytoplasm. SMAD4 plays a key role in TGF-β-mediated family signal transduction and regulating cell proliferation, differentiation, apoptosis and immune regulation.
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Staining Tissue
- As Figure shows:
Pancreatic cancer tissue stained with SMAD4/DPC4
Specification
|
CODE |
WORKING SOLUTION |
CONCENTRATED SOLUTION |
||||
|
CSR-0260 |
SPECIFICATION |
1ml |
3ml |
6ml |
0.1ml |
0.2ml |
More Info
Clone: BSB-63
Source: Rabbit
Localization: Cytoplasm/Nucleus
Pretreatment: Thermal remediation
Applicable tissue: Paraffin section
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