In aerobic respiration, succinate dehydrogenase catalyzes succinate and ubiquinone to be fumarate and panthenol respectively. SDH protein is composed of four subunits: yellow pigment subunit (SDHA), iron-sulfur protein (SDHB), and two membrane-bound subunits (SDHC and SDHD). Mutations in these subunits can cause different mitochondrial dysfunctions.
[As Figure shows]
Pheochromocytoma tissue stained with SDHB
In aerobic respiration, succinate dehydrogenase catalyzes succinate and ubiquinone to be fumarate and panthenol respectively. SDH protein is composed of four subunits: yellow pigment subunit (SDHA), iron-sulfur protein (SDHB), and two membrane-bound subunits (SDHC and SDHD). Mutations in these subunits can cause different mitochondrial dysfunctions.
Product Name | SDHB(21A11AE7),MMab |
Catalog No. | CSM-0270 |
Intended Use | IVD, RUO |
Species Reactivity | Human; others not tested |
Cellular Localization | Cytoplasm / Nucleus |
Antibody Type | Mouse Monoclonal |
Clone | 21A11AE7 |
Format and Volume | Ready-to-use: 1mL, 3mL, 6mL Concentrated: 0.1mL, 0.2mL and 1mL |
IVD Datasheet (IFU) | ↕️ Download |
RUO Datasheet (IFU) | ↕️ Download |
SDS sheet | check with sales |
Store at 2~8°C. Avoid freezing.
Maintain temperature below room temperature during transport, ensuring it does not exceed one week.