The connecting family includes α-catenin, β-catenin, γ-cateninand P120 Catenin. P120 Catenin P120 Catenin is linked to E-Cadherin in the plasma next to the cell membrane to form a complex that is stable and tightly connected. A lack of E-Cadherin can lead to the accumulation of P120 Catenin in the cytoplasm. Soin lobular carcinoma of breast,a large amount of P120 Catenin in the cytoplasm is shown. However, in ductalcarcinoma of the breast, a small amount of P120Catenin is shown in membrane, not to found the accumulation in the cytoplasm. Therefore, this antibody can be used for the identification of ductal source tumors or lobular source tumors of breast.
[As Figure shows]
Breast cancer tissue stained with P120
The connecting family includes α-catenin, β-catenin, γ-cateninand P120 Catenin. P120 Catenin P120 Catenin is linked to E-Cadherin in the plasma next to the cell membrane to form a complex that is stable and tightly connected. A lack of E-Cadherin can lead to the accumulation of P120 Catenin in the cytoplasm. Soin lobular carcinoma of breast,a large amount of P120 Catenin in the cytoplasm is shown. However, in ductalcarcinoma of the breast, a small amount of P120Catenin is shown in membrane, not to found the accumulation in the cytoplasm. Therefore, this antibody can be used for the identification of ductal source tumors or lobular source tumors of breast.
Product Name | p120(EP66),Rmab |
Catalog No. | CPR-0181 |
Intended Use | IVD, RUO |
Species Reactivity | Human; others not tested |
Cellular Localization | Cytoplasm / Nucleus |
Antibody Type | Rabbit Monoclonal |
Clone | EP66 |
Format and Volume | Ready-to-use: 1mL, 3mL, 6mL Concentrated: 0.1mL, 0.2mL and 1mL |
IVD Datasheet (IFU) | ↕️ Download |
RUO Datasheet (IFU) | ↕️ Download |
SDS sheet | check with sales |
Store at 2~8°C. Avoid freezing.
Maintain temperature below room temperature during transport, ensuring it does not exceed one week.
CODE |
WORKING SOLUTION |
CONCENTRATED SOLUTION |
||||
CPR-0181 |
SPECIFICATION |
1ml |
3ml |
6ml |
0.1ml |
0.2ml |
Clone: EP66
Source: Rabbit
Localization: Cytoplasm/Membrane
Pretreatment : Thermal remediation
Applicable tissue: Paraffin section