Ksp-Cadherin(MRQ-33),MMab

Ksp-cadherin is a new member of the family of cadherins. The protein has kidney specificity. In kidney tissue, Ksp-cadherin only expresses in the epithelial membrane and the epithelial of the kidney tube. And does not express in the. renal cells, internephalic cells and blood vessels Many different cadherins(E-cadherins, N-cadherins ,cadherins- δ and so on) were found and validated in renal cell tumors. The absence of some cadherins may be associated with tumor dedifferentiation and lymph node metastasis. Shen et al. research data show that Ksp-cadherin has up to 100% sensitivity (13/13) in renal cell carcinoma and 95% sensitivity (19/20) in renal acidophilic cell adenomas.

Staining Tissue

[As Figure shows]

Kidney tissue stained with Ksp-cadherin

[Intended Use]

Ksp-cadherin is a new member of the family of cadherins. The protein has kidney specificity. In kidney tissue, Ksp-cadherin only expresses in the epithelial membrane and the epithelial of the kidney tube. And does not express in the. renal cells, internephalic cells and blood vessels Many different cadherins(E-cadherins, N-cadherins ,cadherins- δ and so on) were found and validated in renal cell tumors. The absence of some cadherins may be associated with tumor dedifferentiation and lymph node metastasis. Shen et al. research data show that Ksp-cadherin has up to 100% sensitivity (13/13) in renal cell carcinoma and 95% sensitivity (19/20) in renal acidophilic cell adenomas.

 

[Specifications]

Product Name Ksp-Cadherin(MRQ-33),MMab
Catalog No. CKM-0040
Intended Use IVD, RUO
Species Reactivity Human; others not tested
Cellular Localization Cytoplasm / Nucleus
Antibody Type Mouse Monoclonal
Clone MRQ-33
Format and Volume Ready-to-use: 1mL, 3mL, 6mL   Concentrated: 0.1mL, 0.2mL and 1mL 

 

[Datasheets & SDS]

IVD Datasheet (IFU) ↕️ Download 
RUO Datasheet (IFU) ↕️ Download 
SDS sheet check with sales 

 

[Storage and Validity]

Store at 2~8°C. Avoid freezing. 
Maintain temperature below room temperature during transport, ensuring it does not exceed one week.

 

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