Inhibin and activators are members of the family of the conversion growth factor β (TGF beta) of cytokines. Inhibin are hetero-dimer consisting of the general α -subunit linked withβ A subuni (α -βA, forming inhibitor A) orβ-B subunit (α -βB, forming inhibitor B).The β sub-unit which shared by activators and inhibitors is the β sub-unit ‘s homologous dimer or hetero- dimer. Thus to create activin A(βA-βA), activatorA B(βA-βB) or activator B (βB-βB).The expression of α -subunit and inhibitors is more limited than β-subunit and activin. Inhibitors and activin play a role in regulating the secretion of pituitary follicle stimulating hormone (FSH). Inhibitors and activin act opposite each other, inhibitors inhibit FSH secretion and activin stimulates FSH secretion. Inhibitors are secreted by female follicle granules and male testicular support (Sertoli) cells.Iinhibitors have a local regulatory effect in various tissues, including the brain, adrenal glands, bone marrow, fetus and placenta expect to ovaries.
Adrenalgland tissue stained with Inhibin-α
This antibody is intended for use in Immunohistochemical applications on formalin-fixed paraffin-embedded tissues (FFPE). The clinical interpretation of any staining or its absence should be complemented by morphological studies using proper controls and should be evaluated within the context of the patient’s clinical history and other diagnostic tests by a qualified pathologist.
Product Name | Inhibin, alpha (C6H12), MMab |
Catalog No. | CIM-0150 |
Intended Use | IVD, RUO |
Species Reactivity | Human; others not tested |
Cellular Localization | Cytoplasm |
Antibody Type | Mouse Monoclonal |
Clone | C6H12 |
Format and Volume | Ready-to-use: 1mL, 3mL, 6mL Concentrated: 0.1mL, 0.2mL and 1mL |
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IVD Datasheet (IFU) | ↕️ Download |
RUO Datasheet (IFU) | ↕️ Download |
SDS sheet | check with sales |
Store at 2~8°C. Avoid freezing.
Maintain temperature below room temperature during transport, ensuring it does not exceed one week.