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GATA3(L50-823),MMab
GATA3, is a zinc finger transcription factor that plays an important role in promoting and guiding cell proliferation, development and differentiation in many tissues and cell types which binds to the DNA sequence (A/T)GATA(A/G). GATA3 has been reported to be expressed in breast cancer and urothelial carcinoma, while it is rarely expressed in other tumors. GATA3 was expressed in all breast lobular carcinomas and 91% invasive ductal carcinoma (grade I,100%;Level, 89%;At the same time, the expression of GATA3 was positively correlated with ER、 PR and negatively correlated with HER-2 in breast cancer. GATA 3 is also expressed in urothelial carcinoma, especially in invasive and high-grade tumors. Therefore, GATA3 can be utilized as a differential diagnosis of urothelial carcinoma and tumors of unknown origin.
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Staining Tissue
[As Figure shows]
Breast carcinoma tissue stained with GATA3
[Intended Use]
GATA3, is a zinc finger transcription factor that plays an important role in promoting and guiding cell proliferation, development and differentiation in many tissues and cell types which binds to the DNA sequence (A/T)GATA(A/G). GATA3 has been reported to be expressed in breast cancer and urothelial carcinoma, while it is rarely expressed in other tumors. GATA3 was expressed in all breast lobular carcinomas and 91% invasive ductal carcinoma (grade I,100%;Level, 89%;At the same time, the expression of GATA3 was positively correlated with ER、 PR and negatively correlated with HER-2 in breast cancer. GATA 3 is also expressed in urothelial carcinoma, especially in invasive and high-grade tumors. Therefore, GATA3 can be utilized as a differential diagnosis of urothelial carcinoma and tumors of unknown origin.
[Specifications]
| Product Name | GATA3(L50-823),MMab |
| Catalog No. | CGM-0130 |
| Intended Use | IVD, RUO |
| Species Reactivity | Human; others not tested |
| Cellular Localization | Cytoplasm / Nucleus |
| Antibody Type | Mouse Monoclonal |
| Clone | L50-823 |
| Format and Volume | Ready-to-use: 1mL, 3mL, 6mL Concentrated: 0.1mL, 0.2mL and 1mL |
[Datasheets & SDS]
| IVD Datasheet (IFU) | ↕️ Download |
| RUO Datasheet (IFU) | ↕️ Download |
| SDS sheet | check with sales |
[Storage and Validity]
Store at 2~8°C. Avoid freezing.
Maintain temperature below room temperature during transport, ensuring it does not exceed one week.
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