Cytokeratin 20(Ks20.8),MMab

It has been proved that CK20 is almost completely confined to the mekerl cells of gastrointestinal epithelium, urinary tract epithelium and skin. CK20 is less acidic than other type I keratin and is of concern due to its limited expression in tissues. In normal tissue, CK20 is expressed in the intestinal glandular epithelium, gastric microconcave epithelium.Many endocrine cells in the upper part of the pyloric gland, the epithelium of the urinary tract and the Merkel cells in the epithelium. It has been reported that the expression of CK20 in different cancer tissues is significantly different. The tumors expressing CK20 are derived from the normal epithelium itself that expresses CK20 only.

Staining Tissue

[As Figure shows]

Adenocarcinoma tissue stained with CK20.

[Intended Use]

It has been proved that CK20 is almost completely confined to the mekerl cells of gastrointestinal epithelium, urinary tract epithelium and skin. CK20 is less acidic than other type I keratin and is of concern due to its limited expression in tissues. In normal tissue, CK20 is expressed in the intestinal glandular epithelium, gastric microconcave epithelium.Many endocrine cells in the upper part of the pyloric gland, the epithelium of the urinary tract and the Merkel cells in the epithelium. It has been reported that the expression of CK20 in different cancer tissues is significantly different. The tumors expressing CK20 are derived from the normal epithelium itself that expresses CK20 only.

 

[Specifications]

Product Name Cytokeratin 20(Ks20.8),MMab
Catalog No. CCM-1110
Intended Use IVD, RUO
Species Reactivity Human; others not tested
Cellular Localization Cytoplasm / Nucleus
Antibody Type Mouse Monoclonal
Clone Ks20.8
Format and Volume Ready-to-use: 1mL, 3mL, 6mL   Concentrated: 0.1mL, 0.2mL and 1mL 

 

[Datasheets & SDS]

IVD Datasheet (IFU) ↕️ Download 
RUO Datasheet (IFU) ↕️ Download 
SDS sheet check with sales 

 

[Storage and Validity]

Store at 2~8°C. Avoid freezing. 
Maintain temperature below room temperature during transport, ensuring it does not exceed one week.

 

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