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Carbonic Anhydrase 9(EP161),RMab
Carbonic anhydrase (CA) is an enzyme that assists in the rapid synthesis of Carbonic acid, protons, and bicarbonate ions from carbon dioxide and water.It is highly expressed in mammalian tissues.There are many genes that induce hypoxia by hif-1 induction, and ca-9 is the most important of these genes due to its stability and location in the membrane.Carbonic anhydrase regulates the PH value in normal tissues by regulating hydrogen ions. The change of PH can reflect the cell death under hypoxia. The high expression of ca-9 leads to the increase of cell death under hypoxia.Therefore, ca-9 is a reliable histochemical marker reflecting hypoxia.
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Staining Tissue
[As Figure shows]
Renal cell carcinoma tissue stained with CAIX
[Intended Use]
Carbonic anhydrase (CA) is an enzyme that assists in the rapid synthesis of Carbonic acid, protons, and bicarbonate ions from carbon dioxide and water.It is highly expressed in mammalian tissues.There are many genes that induce hypoxia by hif-1 induction, and ca-9 is the most important of these genes due to its stability and location in the membrane.Carbonic anhydrase regulates the PH value in normal tissues by regulating hydrogen ions. The change of PH can reflect the cell death under hypoxia. The high expression of ca-9 leads to the increase of cell death under hypoxia.Therefore, ca-9 is a reliable histochemical marker reflecting hypoxia.
[Specifications]
| Product Name | Carbonic Anhydrase 9(EP161),RMab |
| Catalog No. | CCR-0231 |
| Intended Use | IVD, RUO |
| Species Reactivity | Human; others not tested |
| Cellular Localization | Cytoplasm / Nucleus |
| Antibody Type | Rabbit Monoclonal |
| Clone | EP161 |
| Format and Volume | Ready-to-use: 1mL, 3mL, 6mL Concentrated: 0.1mL, 0.2mL and 1mL |
[Datasheets & SDS]
| IVD Datasheet (IFU) | ↕️ Download |
| RUO Datasheet (IFU) | ↕️ Download |
| SDS sheet | check with sales |
[Storage and Validity]
Store at 2~8°C. Avoid freezing.
Maintain temperature below room temperature during transport, ensuring it does not exceed one week.
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