T-cell intracytoplasmic antigen (TIA-1) is a 17kDa intracytoplasmic granule-associated protein, expressed in cells that are prone to cytolysis, recently named GMP-17 (17kDa granule membrane protein). This molecule may be related to the molecular cascade of FAS (CD95) -mediated apoptotic signaling. In hematopoietic cell lines, this antibody reacts with 90% CD16 positive, 50-60% CD8 positive, and 10% CD4 positive lymphocytes in normal peripheral blood. It also reacts with almost all monocytes and granulocytes, CD4-positive activated T cell line, activated NK cell line and Con-A activated thymocytess, but not with B cell line.
[As Figure shows]
Tonsil tissue stained with TIA-1
T-cell intracytoplasmic antigen (TIA-1) is a 17kDa intracytoplasmic granule-associated protein, expressed in cells that are prone to cytolysis, recently named GMP-17 (17kDa granule membrane protein). This molecule may be related to the molecular cascade of FAS (CD95) -mediated apoptotic signaling. In hematopoietic cell lines, this antibody reacts with 90% CD16 positive, 50-60% CD8 positive, and 10% CD4 positive lymphocytes in normal peripheral blood. It also reacts with almost all monocytes and granulocytes, CD4-positive activated T cell line, activated NK cell line and Con-A activated thymocytess, but not with B cell line.
Product Name | TIA-1(2G9A10F5),MMab |
Catalog No. | CTM-0220 |
Intended Use | IVD, RUO |
Species Reactivity | Human; others not tested |
Cellular Localization | Cytoplasm / Nucleus |
Antibody Type | Mouse Monoclonal |
Clone | 2G910F5 |
Format and Volume | Ready-to-use: 1mL, 3mL, 6mL Concentrated: 0.1mL, 0.2mL and 1mL |
IVD Datasheet (IFU) | ↕️ Download |
RUO Datasheet (IFU) | ↕️ Download |
SDS sheet | check with sales |
Store at 2~8°C. Avoid freezing.
Maintain temperature below room temperature during transport, ensuring it does not exceed one week.