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In aerobic respiration, succinate dehydrogenase catalyzes succinate and ubiquinone to be fumarate and panthenol respectively. SDH protein is composed of four subunits: yellow pigment subunit (SDHA), iron-sulfur protein (SDHB), and two membrane-bound subunits (SDHC and SDHD). Mutations in these subunits can cause different mitochondrial dysfunctions.
[As Figure shows]
Pheochromocytoma tissue stained with SDHB
In aerobic respiration, succinate dehydrogenase catalyzes succinate and ubiquinone to be fumarate and panthenol respectively. SDH protein is composed of four subunits: yellow pigment subunit (SDHA), iron-sulfur protein (SDHB), and two membrane-bound subunits (SDHC and SDHD). Mutations in these subunits can cause different mitochondrial dysfunctions.
| Product Name | SDHB(21A11AE7),MMab |
| Catalog No. | CSM-0270 |
| Intended Use | IVD, RUO |
| Species Reactivity | Human; others not tested |
| Cellular Localization | Cytoplasm / Nucleus |
| Antibody Type | Mouse Monoclonal |
| Clone | 21A11AE7 |
| Format and Volume | Ready-to-use: 1mL, 3mL, 6mL Concentrated: 0.1mL, 0.2mL and 1mL |
| IVD Datasheet (IFU) | ↕️ Download |
| RUO Datasheet (IFU) | ↕️ Download |
| SDS sheet | check with sales |
Store at 2~8°C. Avoid freezing.
Maintain temperature below room temperature during transport, ensuring it does not exceed one week.