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HMB-45(HMB45),MMab
HMB45 antigens are also used to identify retinal pigment epithelial (RPE), but the literature reports that it reacts only to RPE before birth and during a short period of infancy. Its reaction to intradermal nevus and normal melanin and non-melanocytes in adults was not observed. Besides, They were negative in epithelial, lymphatic, glial and mesenchymal tumor cells. The clone is detailed in the literature, indicating that it can mark the intracellular antigens of most melanomas and other tumors with melanoma as well as melanoma cell differentiation characteristics. The document also reports that the clone reacts with the junctional nevus and blue nevus cells.
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Staining Tissue
[As Figure shows]
Human metastatic melanoma tissue stained with Melanoma Marker(CD63)
[Intended Use]
HMB45 antigens are also used to identify retinal pigment epithelial (RPE), but the literature reports that it reacts only to RPE before birth and during a short period of infancy. Its reaction to intradermal nevus and normal melanin and non-melanocytes in adults was not observed. Besides, They were negative in epithelial, lymphatic, glial and mesenchymal tumor cells. The clone is detailed in the literature, indicating that it can mark the intracellular antigens of most melanomas and other tumors with melanoma as well as melanoma cell differentiation characteristics. The document also reports that the clone reacts with the junctional nevus and blue nevus cells.
[Specifications]
| Product Name | HMB-45(HMB45),MMab |
| Catalog No. | CMM-0150 |
| Intended Use | IVD, RUO |
| Species Reactivity | Human; others not tested |
| Cellular Localization | Cytoplasm / Nucleus |
| Antibody Type | Mouse Monoclonal |
| Clone | HMB45 |
| Format and Volume | Ready-to-use: 1mL, 3mL, 6mL Concentrated: 0.1mL, 0.2mL and 1mL |
[Datasheets & SDS]
| IVD Datasheet (IFU) | ↕️ Download |
| RUO Datasheet (IFU) | ↕️ Download |
| SDS sheet | check with sales |
[Storage and Validity]
Store at 2~8°C. Avoid freezing.
Maintain temperature below room temperature during transport, ensuring it does not exceed one week.
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