Granulase is an exogenous serine protease produced by cytotoxic T cells and cytoplasmic particles of natural killer cells. Their role is to induce the natural apoptosis of the infected cells, thus destroying the infected cells. Granulase antibodies are used to detect natural killer cells, T-cell lymphoma, and mesodestatic large cell lymphoma. In Hodgkin's lymphoma, the presence of high percentages of toxic T-cells is a poor prognostic indicator.
Neck lymphoma tissue stained with GranzymeB(GrB)
Granulase is an exogenous serine protease produced by cytotoxic T cells and cytoplasmic particles of natural killer cells. Their role is to induce the natural apoptosis of the infected cells, thus destroying the infected cells. Granulase antibodies are used to detect natural killer cells, T-cell lymphoma, and mesodestatic large cell lymphoma. In Hodgkin’s lymphoma, the presence of high percentages of toxic T-cells is a poor prognostic indicator.
Product Name | Granzyme B(EP230),RMab |
Catalog No. | CGR-0211 |
Intended Use | IVD, RUO |
Species Reactivity | Human; others not tested |
Cellular Localization | Cytoplasm / Nucleus |
Antibody Type | Rabbit Monoclonal |
Clone | EP230 |
Format and Volume | Ready-to-use: 1mL, 3mL, 6mL Concentrated: 0.1mL, 0.2mL and 1mL |
IVD Datasheet (IFU) | ↕️ Download |
RUO Datasheet (IFU) | ↕️ Download |
SDS sheet | check with sales |
Store at 2~8°C. Avoid freezing.
Maintain temperature below room temperature during transport, ensuring it does not exceed one week.