Granzyme B(EP230),RMab

Granulase is an exogenous serine protease produced by cytotoxic T cells and cytoplasmic particles of natural killer cells. Their role is to induce the natural apoptosis of the infected cells, thus destroying the infected cells. Granulase antibodies are used to detect natural killer cells, T-cell lymphoma, and mesodestatic large cell lymphoma. In Hodgkin's lymphoma, the presence of high percentages of toxic T-cells is a poor prognostic indicator.

Staining Tissue

[As Figure shows]

Neck lymphoma tissue stained with GranzymeB(GrB)

[Intended Use]

Granulase is an exogenous serine protease produced by cytotoxic T cells and cytoplasmic particles of natural killer cells. Their role is to induce the natural apoptosis of the infected cells, thus destroying the infected cells. Granulase antibodies are used to detect natural killer cells, T-cell lymphoma, and mesodestatic large cell lymphoma. In Hodgkin’s lymphoma, the presence of high percentages of toxic T-cells is a poor prognostic indicator.

 

[Specifications]

Product Name Granzyme B(EP230),RMab
Catalog No. CGR-0211
Intended Use IVD, RUO
Species Reactivity Human; others not tested
Cellular Localization Cytoplasm / Nucleus
Antibody Type Rabbit Monoclonal
Clone EP230
Format and Volume Ready-to-use: 1mL, 3mL, 6mL   Concentrated: 0.1mL, 0.2mL and 1mL 

 

[Datasheets & SDS]

IVD Datasheet (IFU) ↕️ Download 
RUO Datasheet (IFU) ↕️ Download 
SDS sheet check with sales 

 

[Storage and Validity]

Store at 2~8°C. Avoid freezing. 
Maintain temperature below room temperature during transport, ensuring it does not exceed one week.

 

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