CD11c is a member of the integrin family of adhesive proteins.It has been reported that CD11c is expressed in normal tissues, mainly in myeloid cells such as myeloid granulocytes of the bone marrow,promyelocytic, metamyelocyte,none-lobulated and lobulated neutrophils. As well as in tissue of macrophages and monocytes,it expressed at high levels,but it is at low levels in granulocytes.It has also been reported in the literature to be expressed in NK cells, activated T cells, and lymphoid cell lines, including hair cell leukaemia and some finger-like dendritic cells.The expression of CD11c antigen is a practical marker of monocyte differentiation in the classification of acute myeloid leukemia and a practical indicator for the identification of hair cell leukemia.
Tonsil tissue stained with CD11c(Mouse)
CD11c is a member of the integrin family of adhesive proteins.It has been reported that CD11c is expressed in normal tissues, mainly in myeloid cells such as myeloid granulocytes of the bone marrow,promyelocytic, metamyelocyte,none-lobulated and lobulated neutrophils. As well as in tissue of macrophages and monocytes,it expressed at high levels,but it is at low levels in granulocytes.It has also been reported in the literature to be expressed in NK cells, activated T cells, and lymphoid cell lines, including hair cell leukaemia and some finger-like dendritic cells.The expression of CD11c antigen is a practical marker of monocyte differentiation in the classification of acute myeloid leukemia and a practical indicator for the identification of hair cell leukemia.
Product Name | CD11c(5D11),MMab |
Catalog No. | CCM-0400 |
Intended Use | IVD, RUO |
Species Reactivity | Human; others not tested |
Cellular Localization | Cytoplasm / Nucleus |
Antibody Type | Mouse Monoclonal |
Clone | 5D11 |
Format and Volume | Ready-to-use: 1mL, 3mL, 6mL Concentrated: 0.1mL, 0.2mL and 1mL |
IVD Datasheet (IFU) | ↕️ Download |
RUO Datasheet (IFU) | ↕️ Download |
SDS sheet | check with sales |
Store at 2~8°C. Avoid freezing.
Maintain temperature below room temperature during transport, ensuring it does not exceed one week.