-
-
SHOP
PRODUCT CATEGORY
CONTACT US
Ki-67(C3G4), MMab
Ki67 is a cell proliferation marker that is closely related to the cell cycle. There is expression in G1, S, G2, M period,there is no expression in G0 period. Its proliferation index is closely related to the degree of separation, leaching metastasis and prognosis of many tumors. The Ki67 antigen is a nuclear protein which is expressed in all active parts of the cell cycle (G1, S, G2 and mitosis) but is absent in resting cells (G0). In contrast to many other cell cycle-associated proteins, the Ki67 antigen is consistently absent in quiescent cells and is not detectable during DNA repair processes. Thus, the presence of Ki67 antigen is strictly associated with the cell cycle and confined to the nucleus, suggesting an important role in the maintenance and/or regulation of the cell division cycle.
Chat
message
Quote
Download
Photo Staining Tissue
[Intended Use]
This antibody is intended for use in Immunohistochemical applications on formalin-fixed paraffin-embedded tissues (FFPE). The clinical interpretation of any staining or its absence should be complemented by morphological studies using proper controls and should be evaluated within the context of the patient’s clinical history and other diagnostic tests by a qualified pathologist.
[Specifications]
| Product Name | Ki-67 (C3G4), MMab |
| Catalog No. | CKM-0032 |
| Intended Use | IVD, RUO |
| Species Reactivity | Human; others not tested |
| Cellular Localization | Nucleus |
| Antibody Type | Mouse Monoclonal |
| Clone | C3G4 |
| Format and Volume | Ready-to-use: 1mL, 3mL, 6mL Concentrated: 0.1mL, 0.2mL and 1mL |
| Shop Online | 🛒 Buy now |
[Datasheets & SDS]
| IVD Datasheet (IFU) | ↕️ Download |
| RUO Datasheet (IFU) | ↕️ Download |
| SDS sheet | check with sales |
[Storage and Validity]
Store at 2~8°C. Avoid freezing.
Maintain temperature below room temperature during transport, ensuring it does not exceed one week.
[Reference]
1. Key G, et al. New Ki-67-equivalent murine monoclonal antibodies (MIB 1-3) generated against bacterially expressed parts of the Ki-67 cDNA containing three 62 base pair repetitive elements encoding for the Ki-67 epitope. Lab Invest. 1993 Jun;68 (6):629-36.
2. Jansen RL, et al. MIB-1 labelling index is an independent prognostic marker in primary breast cancer. Br J Cancer. 1998 Aug; 78(4):460-5.
3. Goodson WH 3rd, et al. The functional relationship between in vivo bromodeoxyuridine labeling index and Ki-67 proliferation index in human breast cancer. Breast Cancer Res Treat. 1998 May; 49(2):155-64.
4. Center for Disease Control Manual. Guide: Safety Management, NO. CDC-22, Atlanta, GA. April 30, 1976 “Decontamination of Laboratory Sink Drains to Remove Azide Salts.”
5. Clinical and Laboratory Standards Institute (CLSI). Protection of Laboratory Workers from Occupationally Acquired Infections; Approved Guideline-Fourth Edition CLSI document M29-A4 Wayne, PA 2014.
Related Product
