IHC

INSTRUMENT

MOLECULAR

HISTOLOGY

CYTOLOGY

DIGITAL PATHOLOGY

Screening

IHC Automation

PRIMARY ANTIBODY

MICROSTACKER™ DETECTION SYSTEMS

MMR

MULTIPLEX IHC

MULTIPLEX IF

FAST FROZEN IHC

ANCILLARIES

A total of 160 datas

Alpha-1-Fetoprotein (C1B1),MMab

Alpha-Fetoprotein (AFP) is a 70 kDa glycoprotein that is normally produced during fetal development bythe liver and yolk sac. In adult pathology, elevated AFP expression is a hallmark of hepatocellular carcinoma (HCC) and certain germ cell tumors, particularly yolk sac tumors. AFP IHC is a critical component in the diagnostic workup of liver masses and is used to differentiate HCC from other primary or metastatic liver malignancies.

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ACTH (Polyclonal), RPab

Adrenocorticotropic Hormone (ACTH) is a 39-amino acid peptide hormone produced by the anteriorpituitary gland. ACTH antibody is a useful tool in the classification of pituitary adenomas and is instrumental in the differential diagnosis of ectopic ACTH-producing tumors. It specifically labels corticotrophs in the normal pituitary and is a key marker for identifying ACTH- secreting cells in various pathological conditions.

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34βE12/P63/AMACR Detection Kit (Immunocytochemistry)

This kit is used for differential diagnosis of normal prostate, prostate intraepithelial neoplasia (PIN) and prostate cancer. It adopts immunohistochemical double staining detection technology and multiple antibody combination technology. By one staining process, three target antigens can be simultaneously detected on the same prostate lesion tissue section, namely 34βE12, p63 and AMACR. 34βE12 is a high molecular weight cytokeratin expressed in the basal cells of the benign prostate acinar.

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TRPS1(EPR16171),RMab

Trichorhinophalangeal syndrome type 1 (TRPS1) as a specific gene for breast carcinoma across 31 solid tumor types. Moreover, high mRNA level of TRPS1 was found in all four subtypes of breast carcinoma including ER/PR-positive luminal A and B types, HER2-positive type, and basal-type/TNBC. We then analyzed TRPS1 expression in 479 cases of various types of breast cancer using immunochemistry staining, and found that TRPS1 and GATA3 had comparable positive expression in ER-positive (98% vs. 95%) and HER2-positive (87% vs. 88%) breast carcinomas. However, TRPS1 which was highly expressed in TNBC, was significantly higher than GATA3 expression in metaplastic (86% vs. 21%) and nonmetaplastic (86% vs. 51%) TNBC. In addition, TRPS1 expression was evaluated in 1234 cases of solid tumor from different organs. In contrast to the high expression of GATA3 in urothelial carcinoma, TRPS1 showed no or little expression in urothelial carcinomas or in other tumor types including lung adenocarcinoma, pancreatic adenocarcinoma, colon and gastric adenocarcinoma, renal cell carcinoma, melanoma, and ovarian carcinoma.

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