GATA1, a member of the GATA family, was first discovered and expressed in the early erythrocytes,megakaryocyte,eosnophils,mastocyte, testicular substrate Sertoli cell, non-hematopoietic embryonic stem cells. The transcription factor GATA1 plays an important biological role in the proliferation and differentiation of normal red blood cells and controls the differentiation of megakaryocyte, mast cells and eosinophilic cells.The transcription factor ,GATA1, can interact with many biological macromolecules, such as erythropoietin (EPO) FOG(friend of GATA) GATA2, which plays an important biological effect in the pathogenesis of multiple myeloma and leukemia as well as thrombocytopenia.
Bone marrow megakaryocyte tissue stained with GATA1
รหัส |
โซลูชันการทำงาน |
CONCENTRATED SOLUTION |
||||
CGM-0120 |
ข้อมูลจำเพาะ |
1ml |
3 มล. |
6ml |
0.1ml |
0.2ml |
โคลน: 4F5
แหล่งที่มา: Mouse
การแปล: Nucleus
Pretreatment: Thermal remediation
เนื้อเยื่อที่เกี่ยวข้อง: Paraffin section