Alpha-1-antitrypsin is synthesized in the liver and is present in serum and tissue fluid as a protease inhibitor, especially as an elastase inhibitor.Its main function is to neutralize the release of elastase by neutrophils in the inflammatory response.The deficiency of Alpha-1-antitrypsin may lead to lung failure to inhibit tissue destruction induced by elastase. Alpha-1-antitrypsin deficiency is associated with acinar emphysema and liver disease.In the liver, deficiency of c-1-antitrypsin may cause neonatal hepatitis or cirrhosis of the liver in some individuals during adolescence or adulthood.
Tonsil tissue stained with AAT
КОД |
Рабочее решение |
|||
CAR-0110 |
Спецификация |
1 мл |
3 мл |
6 мл |
Клон: Polyclonal
Источник: Кролик
Локализация: Cytoplasm
Предварительная обработка: Тепловое восстановление
Применимая ткань: Paraffin section/Frozen section