Product Name | DPC4(RBT-SMAD4),RMab |
Clone | RBT-SMAD4 |
Catalog No. | CSR-0261 |
Positive Site | Cytoplasm |
Applicable Tissue | Paraffin section |
Pre-treatment | Heat retrieval |
Format and Volume | Ready-to-use: 1mL, 3mL, 6mL Concentrated: 0.1mL, 0.2mL and 1mL |
DPC4(RBT-SMAD4),RMab
The SMAD4 gene is located on chromosome 18q21. 1. its gene transcript has a total length of 2680 bp and encodes 552 amino acids, resulting in a protein with a relative molecular mass of 60 kDa. The SMAD4 linker region is essential for its interaction with other SMAD proteins, which are key mediators of TGF-B signaling from the cytoplasm to the nucleus. SMAD4 plays a crucial role in signal transduction mediated by the TGF-B family, and is important for regulating cell proliferation, differentiation, apoptosis, and immune modulation.
Intended Use
The SMAD4 gene is located on chromosome 18q21. 1. its gene transcript has a total length of 2680 bp and encodes 552 amino acids, resulting in a protein with a relative molecular mass of 60 kDa. The SMAD4 linker region is essential for its interaction with other SMAD proteins, which are key mediators of TGF-B signaling from the cytoplasm to the nucleus. SMAD4 plays a crucial role in signal transduction mediated by the TGF-B family, and is important for regulating cell proliferation, differentiation, apoptosis, and immune modulation.
[Storage and Validity]
Store at 2~8°C. Avoid freezing.
Maintain temperature below room temperature during transport, ensuring it does not exceed one week.
Specification
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Intended Use
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Specification
