SOX-10(EP268),RMab
SOX-10( SRY-related HMG-box gene 10) is a nuclear transcription factor involved in neural development and melanocyte lineage differentiation. It has recently been established as a sensitive marker for melanoma, including conventional, spindle cell, and desmoplastic subtypes. SOX-10 is expressed in 97% of melanomas and 49% of malignant peripheral nerve sheath tumors. In desmoplastic or spindle cell melanoma, SOX-10 is frequently positive, whereas HMB45 and Melan A are typically negative.
Intended Use
SOX-10( SRY-related HMG-box gene 10) is a nuclear transcription factor involved in neural development and melanocyte lineage differentiation. It has recently been established as a sensitive marker for melanoma, including conventional, spindle cell, and desmoplastic subtypes. SOX-10 is expressed in 97% of melanomas and 49% of malignant peripheral nerve sheath tumors. In desmoplastic or spindle cell melanoma, SOX-10 is frequently positive, whereas HMB45 and Melan A are typically negative.
[Storage and Validity]
Store at 2~8°C. Avoid freezing.
Maintain temperature below room temperature during transport, ensuring it does not exceed one week.
Specification
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Intended Use
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