Glutamine Synthetase (C6E12), MMab
Glutamine synthetase (GS) catalyzes the formation of glutamine from glutamate and ammonia in the mammalian liver. In normal liver tissue, GS expression is restricted to centrilobular hepatocytes (those surrounding the central vein) and is absent in periportal hepatocytes. Glutamine synthetase has been established as a marker for hepatocellular carcinoma (HCC). It is expressed in the majority of HCC cases, including 70% of early-stage HCC and 59% of poorly differentiated HCC.
Intended Use
Glutamine synthetase (GS) catalyzes the formation of glutamine from glutamate and ammonia in the mammalian liver. In normal liver tissue, GS expression is restricted to centrilobular hepatocytes (those surrounding the central vein) and is absent in periportal hepatocytes. Glutamine synthetase has been established as a marker for hepatocellular carcinoma (HCC). It is expressed in the majority of HCC cases, including 70% of early-stage HCC and 59% of poorly differentiated HCC.
[Storage and Validity]
Store at 2~8°C. Avoid freezing.
Maintain temperature below room temperature during transport, ensuring it does not exceed one week.
Specification
Product Name | Glutamine Synthetase (C6E12), MMab |
Clone | C6E12 |
Catalog No. | CGM-0191 |
Positive Site | Cytoplasm |
Applicable Tissue | Paraffin section |
Pre-treatment | Heat retrieval |
Format and Volume | Ready-to-use: 1mL, 3mL, 6mL Concentrated: 0.1mL, 0.2mL and 1mL |
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Intended Use
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Specification
