Bcl-2(124),MMab
Bcl-2 is a key anti-apoptotic protein. The Bcl-2 oncogene, discovered at the t(14;18) chromosomal translocation breakpoint, is a cytogenetic hallmark of follicular lymphoma. High levels of Bcl-2 expression are characteristic of most follicular Iymphomas, making it an indispensable tool for differentiating them from reactive follicular hyperplasia, where germinal centers are typically Bcl-2 negative. The antibody is also expressed in various other B-cell and T-cell lymphoproliferative disorders.
Intended Use
Bcl-2 is a key anti-apoptotic protein. The Bcl-2 oncogene, discovered at the t(14;18) chromosomal translocation breakpoint, is a cytogenetic hallmark of follicular lymphoma. High levels of Bcl-2 expression are characteristic of most follicular Iymphomas, making it an indispensable tool for differentiating them from reactive follicular hyperplasia, where germinal centers are typically Bcl-2 negative. The antibody is also expressed in various other B-cell and T-cell lymphoproliferative disorders.
Storage & Validity
Store at 2~8°C. Avoid freezing.
Maintain temperature below room temperature during transport, ensuring it does not exceed one week.
Specifications
| Product Name | Bcl-2(124),MMab |
| Clone | 124 |
| Catalog No. | CBM-0041 |
| Positive Site | Cytoplasm |
| Applicable Tissue | Paraffin section |
| Pre-treatment | Heat retrieval |
| Format and Volume | Ready-to-use: 1mL, 3mL, 6mL Concentrated: 0.1mL, 0.2mL, 1mL |
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Intended Use
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Specifications
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