ARID1A(EPR13501),RMab
ARID1A (AT-rich interactive domain-containing protein 1A) is a key component of the SWI/SNF chromatin remodeling complex. It functions as a tumor suppressor by regulating gene expression through chromatin modification. Loss of nuclear ARID1A expression is a frequent event in several malignancies, most notably ovarian clear cell carcinoma and endometrioid carcinoma. ARID1A IHC is a valuable tool for identifying these molecular subtypes and is often associated with specific clinical outcomes and potential therapeutic vulnerabilities.
Intended Use
ARID1A (AT-rich interactive domain-containing protein 1A) is a key component of the SWI/SNF chromatin remodeling complex. It functions as a tumor suppressor by regulating gene expression through chromatin modification. Loss of nuclear ARID1A expression is a frequent event in several malignancies, most notably ovarian clear cell carcinoma and endometrioid carcinoma. ARID1A IHC is a valuable tool for identifying these molecular subtypes and is often associated with specific clinical outcomes and potential therapeutic vulnerabilities.
Storage & Validity
Store at 2~8°C. Avoid freezing.
Maintain temperature below room temperature during transport, ensuring it does not exceed one week.
Specifications
| Product Name | ARID1A(EPR13501),RMab |
| Clone | EPR13501 |
| Catalog No. | CAR-0240 |
| Positive Site | Nucleus |
| Applicable Tissue | Paraffin section |
| Pre-treatment | Heat retrieval |
| Format and Volume | Ready-to-use: 1mL, 3mL, 6mL |
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Intended Use
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Specifications
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