CD123(6H6),MMab
CD123, also known as the alpha subunit of the human interleukin-3 (IL-3) receptor, is a type I transmembrane glycoprotein and a member of the cytokine receptor superfamily. CD123 forms a heterodimer with CD131 (the beta subunit of the IL-3 receptor) to constitute the functional IL-3 receptor, in which the alpha subunit confers cytokine specificity while the beta subunit mediates signal transduction. It has been reported that the IL-3 receptor is expressed on monocytes, neutrophils, basophils, eosinophils, megakaryocytes, as well as their proliferating and differentiating precursors. In addition to the hematopoietic system, CD123 is also expressed in Leydig cells of the testis, certain endothelial cells, and cells of the placenta and brain.
Intended Use
CD123, also known as the alpha subunit of the human interleukin-3 (IL-3) receptor, is a type I transmembrane glycoprotein and a member of the cytokine receptor superfamily. CD123 forms a heterodimer with CD131 (the beta subunit of the IL-3 receptor) to constitute the functional IL-3 receptor, in which the alpha subunit confers cytokine specificity while the beta subunit mediates signal transduction. It has been reported that the IL-3 receptor is expressed on monocytes, neutrophils, basophils, eosinophils, megakaryocytes, as well as their proliferating and differentiating precursors. In addition to the hematopoietic system, CD123 is also expressed in Leydig cells of the testis, certain endothelial cells, and cells of the placenta and brain.
Storage & Validity
Store at 2~8°C. Avoid freezing.
Maintain temperature below room temperature during transport, ensuring it does not exceed one week.
Specifications
| Product Name | CD123(6H6),MMab |
| Clone | 6H6 |
| Catalog No. | CCM-0771 |
| Positive Site | Cytoplasm, Membrane |
| Applicable Tissue | Paraffin section |
| Pre-treatment | Heat retrieval |
| Format and Volume | Ready-to-use: 1mL, 3mL, 6mL |
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Intended Use
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Specifications
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