CD71(10F11),MMab

CD71 is a type Il transmembrane glycoprotein with an approximate molecular weight of 180 kDa. It is recognized as the transferrin receptor and consists of two 90 kDa subunits linked by disulfide bonds. CD71 plays a critical role in cell proliferation by regulating iron availability, which is essential for many metabolic pathways. This function is mediated through binding and internalization of iron-transport proteins, primarily transferrin. It has been reported that CD71 is expressed on activated B and T lymphocytes, macrophages, proliferating cells, and metabolically active cells such as neurons.

CD71(10F11),MMab
CD71(10F11),MMab

Intended Use

CD71 is a type Il transmembrane glycoprotein with an approximate molecular weight of 180 kDa. It is recognized as the transferrin receptor and consists of two 90 kDa subunits linked by disulfide bonds. CD71 plays a critical role in cell proliferation by regulating iron availability, which is essential for many metabolic pathways. This function is mediated through binding and internalization of iron-transport proteins, primarily transferrin. It has been reported that CD71 is expressed on activated B and T lymphocytes, macrophages, proliferating cells, and metabolically active cells such as neurons.


Storage & Validity

Store at 2~8°C. Avoid freezing. 

Maintain temperature below room temperature during transport, ensuring it does not exceed one week.

Specifications


Product NameCD71(10F11),MMab
Clone10F11
Catalog No.CCM-0710
Positive SiteCytoplasm, Membrane
Applicable TissueParaffin section
Pre-treatmentHeat retrieval
Format and VolumeReady-to-use: 1mL, 3mL, 6mL
  • Intended Use

  • Specifications

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