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ER Positive and ER Negative What Every Expert Needs to Know

ER Positive and ER Negative What Every Expert Needs to Know

ER positive breast cancer is characterized by the presence of estrogen receptors on the surface of the tumor cells. In this context, estrogen plays a significant role in promoting the growth of these cancer cells.

How Does HER2 Impact Breast Cancer Aggressiveness?

How Does HER2 Impact Breast Cancer Aggressiveness?

HER2, or Human Epidermal growth factor Receptor 2, is a protein that plays a critical role in regulating cell growth and division. It is a member of the HER family of receptors, which are found on the surface of cells. In the context of breast cancer, HER2 is noteworthy due to its role as an oncogene.

What Are the Common Problems in Immunohistochemistry Staining?

What Are the Common Problems in Immunohistochemistry Staining?

Immunohistochemistry (IHC) staining involves a procedure that may encounter obstacles. It's vital to address these issues adeptly to ensure outcomes and preserve the authenticity of your samples. Three common challenges in IHC staining are staining results, excessive background noise, and unspecific staining patterns.

Essential IHC Stains Every Pathologist Should Know

Essential IHC Stains Every Pathologist Should Know

Staining tissues with IHC is a method used in pathology to reveal antigens in tissue samples. This involves a series of steps including preparing the tissue, retrieving the antigen, blocking nonspecific binding, and applying primary antibodies for visualization.

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