HMB45 antigens are also used to identify retinal pigment epithelial (RPE), but the literature reports that it reacts only to RPE before birth and during a short period of infancy. Its reaction to intradermal nevus and normal melanin and non-melanocytes in adults was not observed. Besides, They were negative in epithelial, lymphatic, glial and mesenchymal tumor cells. The clone is detailed in the literature, indicating that it can mark the intracellular antigens of most melanomas and other tumors with melanoma as well as melanoma cell differentiation characteristics. The document also reports that the clone reacts with the junctional nevus and blue nevus cells.
Human metastatic melanoma tissue stained with Melanoma Marker(CD63)
CODICE |
Soluzione di lavoro |
CONCENTRATED SOLUTION |
||||
CMM-0150 |
Specifiche |
1 ml |
3 ml |
6 ml |
0.1ml |
0.2ml |
Clone: HMB45
Fonte: Mouse
Localizzazione: Cytoplasm
Pretreatment: Thermal remediation
Tessuto applicabile: Paraffin section/Frozen section