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Immunoistochimica
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ISTOLOGIA
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MMR panel by IHC-MSH2
MSH2 IHC is particularly important in diagnosing and understanding various genetic conditions and cancers, especially those associated with hereditary mismatch repair deficiency (HMRD), such as Lynch syndrome (hereditary non-polyposis colorectal cancer, or HNPCC). Mutations or abnormalities in MSH2 can result in MMR deficiency, leading to an increased risk of developing colorectal cancer, endometrial cancer, and other malignancies.
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