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Thyroid Peroxidase(TPO)

Thyroid peroxidase (TPO) is an enzyme expressed in the thyroid. TPO oxidizes the iodine ion to form an iodine atom, which binds to the thyroglobulin's tyrosine residues to produce thyroxine (T4) and triiodothyronine (T3). The expression of TPO gene is regulated by thyroid stimulating hormone. In the normal thyroid, TPO shows diffuse in all follicular cells with granular cytoplasmic staining. The expression level of TPO in thyroid cancer is lower than that of normal thyroid and benign thyroid tumors.

Tachoir de tissu

  • Comme le montre la figure:

Lymphocytic thyroiditis tissue stained with TPO

Spécification

CODE

 Solution de travail

CONCENTRATED SOLUTION

CTR-0161

SPÉCIFICATION

1 ml

3 ml

6 ml

0.1ml

0.2ml

Plus d'informations

Cloner:  EP159

Source: Lapin

Localisation: Cytoplasm

Pretreatment:  Thermal remediation

Tissu applicable: Paraffin section

Produit connexe

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