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Immunohistochimie
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MOLÉCULAIRE
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HISTOLOGIE
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SOX-10, anti-rabbit, EP268
SOX-10 (Sry-relaed HMG-BOX gene 10) is a nuclear transcription factor involved in the development of nerves and the differentiation of melanocyte cell lines. It has recently been shown to be a sensitive marker for melanoma (including conventional, fusiform, and connective tissue hyperplasia). SOX-10 is expressed in 97% of melanomas and 49% of malignant schwannomas. SOX-10 is often expressed to be positive in connective tissue hyperplasia and spindle cell melanoma, but negative in HMB45 and MelanA.
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Tachoir de tissu
- Comme le montre la figure:
Malignant melanoma tissue stained with SOX-10
Spécification
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CODE |
Solution de travail |
CONCENTRATED SOLUTION |
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CSR-0180 |
SPÉCIFICATION |
1 ml |
3 ml |
6 ml |
0.1ml |
0.2ml |
Plus d'informations
Cloner: EP268
Source: Lapin
Localisation: Nucleus
Pretreatment: Thermal remediation
Tissu applicable: Paraffin section
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