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Immunohistochimie
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INSTRUMENT
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MOLÉCULAIRE
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HISTOLOGIE
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CYTOLOGIE
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Pathologie numérique
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SMAD4/DPC4
SMAD4 gene is located on chromosome 18q21.1. The gene transcription has a total length of 2680 bp, contains 552 amino acids, and has a relative molecular weight of 60 kD. SMAD4 junction region is necessary for other SMADs to bind to it. SMADs are the key link that TGF-β signal enters nucleus from cytoplasm. SMAD4 plays a key role in TGF-β-mediated family signal transduction and regulating cell proliferation, differentiation, apoptosis and immune regulation.
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Tachoir de tissu
- Comme le montre la figure:
Pancreatic cancer tissue stained with SMAD4/DPC4
Spécification
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CODE |
Solution de travail |
CONCENTRATED SOLUTION |
||||
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CSR-0260 |
SPÉCIFICATION |
1 ml |
3 ml |
6 ml |
0.1ml |
0.2ml |
Plus d'informations
Cloner: BSB-63
Source: Lapin
Localisation: Cytoplasm/Nucleus
Pretreatment: Thermal remediation
Tissu applicable: Paraffin section
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