BOUTIQUE

Mismatch Repair Protein(MLH1)

MLH1 is a mismatched fix protein in molecular weight of about 87kDa size which is usually associated with the occurrence of hereditary non-polypolycinary colon cancer. The functional defects of MLH1 are considered to be an important mechanism for tumor morbidity and are used to determine genetic mutations in colorectal, esophageal, stomach and cervical cancers. The study showed that about 20% of colorectal cancer patients had a mismatch repair protein (MMR) of expression deficiency, while in the distributive colorectal cancer , MLH1 deficiency patients accounted for more than 95% of patients with MMR deficiency.

Tachoir de tissu

  • Comme le montre la figure:

Colon cancer tissue stained with MLH1

Spécification

CODE

 Solution de travail

CONCENTRATED SOLUTION

CMM-0181

SPÉCIFICATION

1 ml

3 ml

6 ml

0.1ml

0.2ml

Plus d'informations

Cloner:  GM011

Source: Mouse

Localisation: Nucleus 

Pretreatment: Thermal remediation

Tissu applicable: Paraffin section

Cloner:  C12A19

Source: Mouse

Localisation: Nucleus 

Pretreatment: Thermal remediation

Tissu applicable: Paraffin section

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