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Producto
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Inmunohistoquímica
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INSTRUMENTO
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MOLECULAR
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HISTOLOGÍA
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CITOLOGÍA
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Patología digital
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Solution
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Apoyo
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Acerca de
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DIRECCIÓN
9430 Key W Ave, Rockville, MD 20850
LEF1
Lymphatic enhancer factor (LEF-1) belongs to the highly migrating family of components, which plays an important role in cell proliferation, differentiation and apoptosis as a transcription factor-mediated of Wnt signaling pathway in the nucleus of the cell.In chronic lymphocytic leukemia, the high expression of LEF-1 is associated with the development of the disease and adverse prognosis. LEF-1 can be detected the positive exprssion of immunohistochemistry in all malignant cells of chronic lymphocytic leukemia or small lymphocytic lymphocytic lymphocytic disease. LEF-1 had 50% positive expression in follicle lymphoma with high differentiation and 38% positive expression in large B-cell lymphoma,but not in mantle cell lymphoma and marginal zone lymphoma.
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Tejido
- Como muestra la figura:
Lymphoma tissue stained with LEF1
Especificación
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CÓDIGO |
Solución de trabajo |
CONCENTRATED SOLUTION |
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CLR-0080 |
ESPECIFICACIÓN |
1 ml |
3 ml |
6 ml |
0.1ml |
0.2ml |
Más información
Clon: EP310
Fuente: Conejo
Localización: Nucleus
Pretreatment: Thermal remediation
Tejido aplicable: Paraffin section/Frozen section
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