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Producto
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Inmunohistoquímica
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INSTRUMENTO
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MOLECULAR
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HISTOLOGÍA
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CITOLOGÍA
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Patología digital
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Solution
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Apoyo
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Contacto
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Teléfono
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DIRECCIÓN
9430 Key W Ave, Rockville, MD 20850
Calcitonin/CT
Calcitonin (CT) is a 32 amino acid peptide synthesized from parietal thyroid follicular cells.It inhibits osteoclast-mediated bone resorption through receptors, reduces calcium uptake in the kidney, and reduces calcium uptake in the intestine.Therefore, the effect of Calcitonin is to cause a decrease in serum calcium, which is the opposite of the effect of parathyroid hormone.Calcitonin gene transcription also encodes Calcitonin gene-related titanium (CGRP), which is considered an effective vasodilator.In parietal thyroid cells, 95% of CT/CGRP is processed and translated to produce CT, but in nerve cells, 99% of CT/CGRP RNA is translated to CGRP.Endocrine neoplasms, medullary thyroid carcinoma (MTC), sporadic (75% of cases), and hereditary (25% of cases) occur in thyroid C cells.
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Tejido
- Como muestra la figura:
Medullary carcinoma of the thyroid tissue stained with Calcitonin/CT
Especificación
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CÓDIGO |
Solución de trabajo |
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CCR-0190 |
ESPECIFICACIÓN |
1 ml |
3 ml |
6 ml |
Más información
Clon: Polyclonal
Fuente: Conejo
Localización: Cytoplasm
Pretratamiento: Remediación térmica
Tejido aplicable: Paraffin section/Frozen section
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