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Immunhistochemie
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Digitale Pathologie
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Calcitonin/CT
Calcitonin (CT) is a 32 amino acid peptide synthesized from parietal thyroid follicular cells.It inhibits osteoclast-mediated bone resorption through receptors, reduces calcium uptake in the kidney, and reduces calcium uptake in the intestine.Therefore, the effect of Calcitonin is to cause a decrease in serum calcium, which is the opposite of the effect of parathyroid hormone.Calcitonin gene transcription also encodes Calcitonin gene-related titanium (CGRP), which is considered an effective vasodilator.In parietal thyroid cells, 95% of CT/CGRP is processed and translated to produce CT, but in nerve cells, 99% of CT/CGRP RNA is translated to CGRP.Endocrine neoplasms, medullary thyroid carcinoma (MTC), sporadic (75% of cases), and hereditary (25% of cases) occur in thyroid C cells.
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Fleckengewebe
- Wie Abbildung zeigt:
Medullary carcinoma of the thyroid tissue stained with Calcitonin/CT
Spezifikation
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CODE |
Arbeitslösung |
|||
|
CCR-0190 |
SPEZIFIKATION |
1ml |
3ml |
6ml |
Weitere Informationen
Klon: Polyclonal
Quelle: Kaninchen
Lokalisierung: Cytoplasm
Vorbehandlung: Wärmeleitsanlage
Anwendbares Gewebe: Paraffin section/Frozen section
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