-
بيت
-
منتج
-
الكيمياء المناعية
-
أداة
-
جزيئي
-
الأنسجة
-
علم الخلايا
-
علم الأمراض الرقمية
-
-
Solution
-
يدعم
-
عن
-
اتصال
فئة المنتج
T-bet
T-bet is a novel transcription factor belonging to the T-box family, which is selectively expressed in Th1 cells. As a specific transcription factor of Th1, it can induce the production of IFN-γ and plays a decisive role in the differentiation of Th1 cells. T-bet is a powerful transcription activator of the IFN-γ gene, can induce and maintain the expression of IL-12Rβ2, and can reverse the effector Th2 during differentiation and the fully differentiated Th2 to Th1. It inhibits the production of Th2 type cytokines such as IL-4, IL-5, IL-13, accompanied by the production of a large amount of IFN -γ. T-bet can be induced and upregulated by IFN-γ during T cell activation. Through a STAT1-dependent pathway, TGF-β can inhibit Th1 differentiation by inhibiting T-bet. The link between T-bet and Th1/Th2 related diseases is coming into focus.
محادثة
رسالة
يقتبس
تلطيخ الأنسجة
- كما يوضح الشكل:
Hair cell leukemia nucleus tissue stained with T-bet
مواصفة
|
شفرة |
حل العمل |
CONCENTRATED SOLUTION |
||||
|
CTR-0100 |
مواصفة |
1 مل |
3 مل |
6 مل |
0.1ml |
0.2ml |
مزيد من المعلومات
استنساخ: MRQ-46
مصدر: أرنب
التوطين: Nucleus
Pretreatment: Thermal remediation
الأنسجة المعمول بها: Paraffin section
المنتج ذي الصلة
